3,625 research outputs found
The Compact Linear ee Collider (CLIC): Physics Potential
The Compact Linear Collider, CLIC, is a proposed ee collider at the
TeV scale whose physics potential ranges from high-precision measurements to
extensive direct sensitivity to physics beyond the Standard Model. This
document summarises the physics potential of CLIC, obtained in detailed
studies, many based on full simulation of the CLIC detector. CLIC covers one
order of magnitude of centre-of-mass energies from 350 GeV to 3 TeV, giving
access to large event samples for a variety of SM processes, many of them for
the first time in ee collisions or for the first time at all. The high
collision energy combined with the large luminosity and clean environment of
the ee collisions enables the measurement of the properties of Standard
Model particles, such as the Higgs boson and the top quark, with unparalleled
precision. CLIC might also discover indirect effects of very heavy new physics
by probing the parameters of the Standard Model Effective Field Theory with an
unprecedented level of precision. The direct and indirect reach of CLIC to
physics beyond the Standard Model significantly exceeds that of the HL-LHC.
This includes new particles detected in challenging non-standard signatures.
With this physics programme, CLIC will decisively advance our knowledge
relating to the open questions of particle physics.Comment: Input to the European Particle Physics Strategy Update on behalf of
the CLIC and CLICdp Collaboration
Measurement of and Higgs production in fusion at a 1.4 TeV CLIC collider
This paper presents the potential measurement at 1.4 TeV CLIC of the
cross-section (times branching ratio) of the Higgs production via fusion
with the Higgs subsequently decaying in ,
, and of the Higgs
production via fusion with the Higgs subsequently decaying in ,
. For the decay the hadronic final state, , and the semi-leptonic final state, , are considered. The results show that
can be measured
with a precision of 18.3% and 6% for the hadronic and semi-leptonic channel,
respectively. can be
measured with a precision of 1.7%. This measurement also contributes to the
determination of the Higgs coupling to the boson, .Comment: Talk presented at the International Workshop on Future Linear
Colliders (LCWS14), Belgrade, Serbia, 6-10 October 201
Performance of the EUDET-type beam telescopes
Test beam measurements at the test beam facilities of DESY have been
conducted to characterise the performance of the EUDET-type beam telescopes
originally developed within the EUDET project. The beam telescopes are equipped
with six sensor planes using MIMOSA26 monolithic active pixel devices. A
programmable Trigger Logic Unit provides trigger logic and time stamp
information on particle passage. Both data acquisition framework and offline
reconstruction software packages are available. User devices are easily
integrable into the data acquisition framework via predefined interfaces.
The biased residual distribution is studied as a function of the beam energy,
plane spacing and sensor threshold. Its standard deviation at the two centre
pixel planes using all six planes for tracking in a 6\,GeV
electron/positron-beam is measured to be
(2.88\,\pm\,0.08)\,\upmu\meter.Iterative track fits using the formalism of
General Broken Lines are performed to estimate the intrinsic resolution of the
individual pixel planes. The mean intrinsic resolution over the six sensors
used is found to be (3.24\,\pm\,0.09)\,\upmu\meter.With a 5\,GeV
electron/positron beam, the track resolution halfway between the two inner
pixel planes using an equidistant plane spacing of 20\,mm is estimated to
(1.83\,\pm\,0.03)\,\upmu\meter assuming the measured intrinsic resolution.
Towards lower beam energies the track resolution deteriorates due to increasing
multiple scattering. Threshold studies show an optimal working point of the
MIMOSA26 sensors at a sensor threshold of between five and six times their RMS
noise. Measurements at different plane spacings are used to calibrate the
amount of multiple scattering in the material traversed and allow for
corrections to the predicted angular scattering for electron beams
Identification of suitable adjuvant for vaccine formulation with the Neospora caninum antigen NcSRS2.
The parasite Neospora caninum is the main cause of abortion in cattle in many countries around the world, so a vaccine is a rational approach method for the control of the disease. An effective vaccine should be able to prevent both, the horizontal and vertical transmission of N. caninum. In this study, the immune vaccinal response of the recombinant protein rNcSRS2 of N. caninum expressed in Pichia pastoris and formulated with water-in-oil emulsion, xanthan gum, and alum hydroxide was assessed in an experimental murine model. Groups of 10 Balb/c mice were subcutaneously inoculated with two doses of prNcSRS2 twenty-one days apart. After the second immunization, four mice from each group were euthanized, and splenocytes were stimulated ex vivo with recombinant protein. The IgG dynamics were evaluated by indirect ELISA, and the splenocytes cytokines transcription by qPCR. All groups elicited specific antibodies against prNcSRS2, with the water-in-oil group showing significantly (p .05) elevated titers compared to the other groups. The prNcSRS2 protein alone did not induce a significant ex vivo splenic transcription level of IFN-c, TNF-a, IL-4, IL-10, and IL-12 cytokines, except for IL-17A, and the adjuvant associations with the prNcSRS2 protein induced different cytokine transcription profiles. The water-inoil emulsion modulated the expression of TNF-a; the xanthan gum modulated IL-4, IL-10, and IL-12; and alum hydroxide modulated IFN-c, TNF-a, IL-4, IL-10, and IL-12. In conclusion, it was found that the association of the recombinant prNcSRS2 protein with different adjuvants induced different levels of specific antibody, and a distinct splenic cytokine profile in an adjuvant-dependent manner. The mechanisms of adjuvancity activity is complex, so adjuvant formulation may help in the design of efficient vaccine to control Neosporosis
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Comparative hazard assessment for protected species in a fire-prone landscape
We conducted a comparative hazard assessment for 325,000 ha in a fire-prone area of southwest Oregon, USA. The landscape contains a variety of land ownerships, fire regimes, and management strategies. Our comparative hazard assessment evaluated the effects of two management strategies on crown fire potential and northern spotted owl (Strix occidentalis caurina) conservation: (1) no action, and (2) active manipulation of hazardous fuels. Model simulations indicated that active management of sites with high fire hazard was more favorable to spotted owl conservation over the long term (75 years) than no management, given our modeling assumptions. Early in the model simulation, young seral stages were mostly responsible for high fire hazard, and active management in young stands tended to perpetuate that hazard. Later in the simulation, older seral stages accounted for most of the high fire hazard and active management could be used to ameliorate that hazard. At any given time period, ⩽8% of the landscape was identified for treatment. Fire hazard fluctuated over time depending on vegetation regeneration, maturation, and response to treatments. Active management resulted in greater numbers of potential spotted owl territories in lower fire hazard conditions, particularly during later years of our simulation. Our results support the contention that short term risks to protected species from active management can be less than longer term risk of no management in fire-prone landscapes. Thus, a short term, risk averse strategy for protected species in fire-prone landscapes may not be the best long term alternative for conservation. We caution that this finding warrants landscape-level field evaluation and structured adaptive management and monitoring prior to broad scale adoption as environmental policy.Keywords: Comparative hazard assessment, Risk analysis, Spotted owls, Fire, Hazardous fuels management, OregonKeywords: Comparative hazard assessment, Risk analysis, Spotted owls, Fire, Hazardous fuels management, Orego
Performance Evaluation of Multiple Cloud Data Centers Allocations for HPC
This paper evaluates the behavior of the Microsoft Azure G5 cloud instance type over multiple Data Centers. The purpose is to identify if there are major differences between them and to help the users choose the best option for their needs. Our results show that there are differences in the network level for the same instance type in different locations and inside the same location at different times. The network performance causes interference in the applications level, as we could verify in our results.This research received funding from the EU H2020 Programme and from MCTI/RNP-Brazil under the HPC4E project, grant agreement
no. 689772. Experiments presented in this paper were carried out using the Grid'5000 testbed, supported by a scientific interest group hosted by Inria and including CNRS, RENATER and several Universities as well as other organizations
(see https://www.grid5000.fr). Additional funding was provided by CAPES and Microsoft.Peer ReviewedPostprint (author's final draft
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